Pub. Date : 2001 Feb
PMID : 11168841
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The effects of cycloheximide and actinomycin on 8-bromo-cAMP (8-Br-cAMP) stimulated vasopressin and oxytocin release from the posterior pituitary and vasopressin mRNA content of the supraoptic nucleus were studied with perifused explants of the hypothalamo-neurohypophyseal system. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
2 | The effects of cycloheximide and actinomycin on 8-bromo-cAMP (8-Br-cAMP) stimulated vasopressin and oxytocin release from the posterior pituitary and vasopressin mRNA content of the supraoptic nucleus were studied with perifused explants of the hypothalamo-neurohypophyseal system. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
3 | The effects of cycloheximide and actinomycin on 8-bromo-cAMP (8-Br-cAMP) stimulated vasopressin and oxytocin release from the posterior pituitary and vasopressin mRNA content of the supraoptic nucleus were studied with perifused explants of the hypothalamo-neurohypophyseal system. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
4 | The effects of cycloheximide and actinomycin on 8-bromo-cAMP (8-Br-cAMP) stimulated vasopressin and oxytocin release from the posterior pituitary and vasopressin mRNA content of the supraoptic nucleus were studied with perifused explants of the hypothalamo-neurohypophyseal system. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
5 | 8-Br-cAMP stimulated vasopressin and oxytocin release from the explant for up to 6 h. Inhibition of protein synthesis by cycloheximide completely suppressed the response to 8-Br-cAMP. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
6 | 8-Br-cAMP stimulated vasopressin and oxytocin release from the explant for up to 6 h. Inhibition of protein synthesis by cycloheximide completely suppressed the response to 8-Br-cAMP. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
7 | When gene transcription was inhibited by actinomycin, vasopressin release was stimulated by 8-Br-cAMP for approximately 2 h, but the response was not sustained. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
8 | Vasopressin mRNA content was not changed by 8-Br-cAMP in the absence or presence of cycloheximide, but it was significantly decreased by simultaneous exposure to 8-Br-cAMP and actinomycin. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
9 | Further evidence that intranuclear release of vasopressin and oxytocin is a prerequisite for cAMP stimulation of vasopressin and oxytocin release was obtained by demonstrating that d(CH2)5-D-Tyr(Me)VAVP, a potent combined V1a/V2/oxytocin receptor antagonist blocked stimulation of vasopressin and oxytocin release by 8-Br-cAMP. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
10 | Further evidence that intranuclear release of vasopressin and oxytocin is a prerequisite for cAMP stimulation of vasopressin and oxytocin release was obtained by demonstrating that d(CH2)5-D-Tyr(Me)VAVP, a potent combined V1a/V2/oxytocin receptor antagonist blocked stimulation of vasopressin and oxytocin release by 8-Br-cAMP. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |
11 | Further evidence that intranuclear release of vasopressin and oxytocin is a prerequisite for cAMP stimulation of vasopressin and oxytocin release was obtained by demonstrating that d(CH2)5-D-Tyr(Me)VAVP, a potent combined V1a/V2/oxytocin receptor antagonist blocked stimulation of vasopressin and oxytocin release by 8-Br-cAMP. | 8-Bromo Cyclic Adenosine Monophosphate | arginine vasopressin | Homo sapiens |