Title : Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation.

Pub. Date : 2001 Jan

PMID : 11165712






2 Functional Relationships(s)
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1 Granulysin was studied in phytohemagglutinin (PHA) stimulated cell lines (donor PBL and CD45RO(+) T cells) by FACS, Western blotting, and RT-PCR after pretreating with cyclosporine A (CSA), azathioprine, mycophenolic acid, and steroids. Azathioprine granulysin Homo sapiens
2 Granulysin levels were unchanged after azathioprine and mycophenolic acid treatment, decreased after treating activated PBL with steroids and cyclosporine A (CSA), and paradoxically, increased (p < 0.05) after treating CD45RO(+) CTL with CSA. Azathioprine granulysin Homo sapiens