Title : Inhibition of cytochrome P450 (CYP450) isoforms by isoniazid: potent inhibition of CYP2C19 and CYP3A.

Pub. Date : 2001 Feb

PMID : 11158730






1 Functional Relationships(s)
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1 Inhibition of one or both CYP2C19 and CYP3A isoforms is the likely mechanism by which INH slows the elimination of coadministered drugs, including phenytoin, carbamazepine, diazepam, triazolam, and primidone. Carbamazepine cytochrome P450 family 3 subfamily A member 4 Homo sapiens