Pub. Date : 2001 Jan
PMID : 11146880
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Under low levels of oxygen (hypoxia), cells expressing wild-type p53 undergo programmed cell death (apoptosis), whereas cells expressing mutations in the p53 gene may survive and express angiogenic growth factors that stimulate tumour vascularization. | Oxygen | tumor protein p53 | Homo sapiens |
2 | In this paper a mathematical model is presented to investigate the effects of alternating periods of hypoxia and normoxia (normal oxygen levels) on a population of wild-type and mutant p53 tumour cells. | Oxygen | tumor protein p53 | Homo sapiens |