Title : Platelet HDL(3) binding sites are not related to integrin alpha(IIb)beta(3) (GPIIb-IIIa).

Pub. Date : 2001 Jan

PMID : 11137079






1 Functional Relationships(s)
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1 Secondly, the HDL(3) binding characteristics (K(d) and B(max) values), the activation of protein kinase C (PKC) and the inhibition of thrombin-induced inositoltriphosphate (IP(3)) formation and calcium (Ca(2+)) mobilization mediated by HDL(3) particles were similar in platelets from control subjects and patients with type I and type II Glanzmann"s thrombasthenia, which are characterized by total and partial lack of GPIIb-IIIa and fibrinogen, respectively. Calcium HDL3 Homo sapiens