Title : Mapping of 5-HT2A receptors and their mRNA in monkey brain: [3H]MDL100,907 autoradiography and in situ hybridization studies.

Pub. Date : 2001 Jan 22

PMID : 11135236






3 Functional Relationships(s)
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1 Mapping of 5-HT2A receptors and their mRNA in monkey brain: [3H]MDL100,907 autoradiography and in situ hybridization studies. Tritium 5-hydroxytryptamine receptor 2A Homo sapiens
2 5-HT2A receptor mRNA was detected in layers III and IV, and in some cases also in layers II and V. In intra- and extra-calcarine areas of striate cortex a five-banded pattern was distinguished, with layers III and IVc-V showing the highest densities of [3H]MDL100,907 labeling. Tritium 5-hydroxytryptamine receptor 2A Homo sapiens
3 Some differences were noted between the distribution of [3H]MDL100,907-labeled 5-HT2A receptors in monkey brain and the previously reported distribution of these receptors in human brain: absence of striosome labeling in monkey striatum and different patterns of neocortical labeling. Tritium 5-hydroxytryptamine receptor 2A Homo sapiens