Pub. Date : 2001 Jan
PMID : 11135061
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells. | Hydrogen Peroxide | transforming growth factor beta 1 | Homo sapiens |
| 2 | A neutralizing anti-TGF-beta antibody was added to test the hypothesis that hydrogen peroxide acts through activation of the TGF-beta pathway to stimulate ECM expression. | Hydrogen Peroxide | transforming growth factor beta 1 | Homo sapiens |
| 3 | CONCLUSIONS: GO-induced hydrogen peroxide production induces TGF-beta1 synthesis and thereby increases ECM gene expression in cultured HMCs. | Hydrogen Peroxide | transforming growth factor beta 1 | Homo sapiens |