Title : Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.

Pub. Date : 2000 Oct

PMID : 11128045






1 Functional Relationships(s)
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1 Production of desmethylranitidine by rat and human liver microsomes was inhibited by tranylcypromine, a-naphthoflavon and quinidine, which are known to inhibit CYP2C19, 1A2 and 2D6, repectively. Quinidine cytochrome P450 family 2 subfamily C member 19 Homo sapiens