Title : Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis.

Pub. Date : 2000 Dec

PMID : 11115077






2 Functional Relationships(s)
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1 The administration of the AT2R antagonist PD123319 or the AT1R antagonist valsartan was associated with attenuation of the increases in both PCNA- and TUNEL-positive cells following Ang II infusion. Valsartan angiotensinogen Rattus norvegicus
2 Ang II infusion was associated with increased osteopontin gene and protein expression, which could be reduced by treatment with either valsartan or PD123319. Valsartan angiotensinogen Rattus norvegicus