Title : Effect of endogenous and exogenous prostaglandin E(2) on interleukin-1 beta-induced cyclooxygenase-2 expression in human airway smooth-muscle cells.

Pub. Date : 2000 Dec

PMID : 11112151






2 Functional Relationships(s)
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1 Inhibition of PGE(2) production with a nonselective COX inhibitor (flurbiprofen, 10 microM) resulted in a significant reduction in IL-1 beta- induced COX-2 expression, supporting a role of endogenous COX metabolites in the modulation of COX-2 expression. Flurbiprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Inhibition of PGE(2) production with a nonselective COX inhibitor (flurbiprofen, 10 microM) resulted in a significant reduction in IL-1 beta- induced COX-2 expression, supporting a role of endogenous COX metabolites in the modulation of COX-2 expression. Flurbiprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens