Title : Role of disulfides and sulfhydryl groups in agonist and antagonist binding in serotonin1A receptors from bovine hippocampus.

Pub. Date : 2000 Dec

PMID : 11100975






1 Functional Relationships(s)
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1 In addition, ligand-binding studies in presence of GTP-gamma-S, a nonhydrolyzable analogue of GTP, indicate that sulfhydryl groups (and disulfide bonds to a lesser extent) are vital for efficient coupling between the 5-HT1A receptor and the G-protein. Guanosine Triphosphate 5-hydroxytryptamine receptor 1A Bos taurus