Pub. Date : 2000 Oct 1
PMID : 11034416
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When compared with wild-type mice, IL-6-/- mice manifest exaggerated inflammation and eosinophilia, increased levels of IL-4, IL-5, and IL-13 protein and mRNA, exaggerated levels of eotaxin, JE/monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and -2, and mRNA, increased bronchoalveolar lavage (BAL) TGF-beta1, and exaggerated airway responses to aerosolized methacholine. | Methacholine Chloride | interleukin 6 | Mus musculus |
| 2 | IL-6 also decreased the expression of endothelial VCAM-1 and airway responsiveness to methacholine in these animals. | Methacholine Chloride | interleukin 6 | Mus musculus |