Pub. Date : 2000 Dec 22
PMID : 11010964
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The relative uptake activity ratios of carnitine to TEA were 1.78, 11.3, and 746 for OCTN1, -2, and -3, respectively, suggesting high specificity of OCTN3 for carnitine and significantly lower carnitine transport activity of OCTN1. | Carnitine | solute carrier family 22 (organic cation transporter), member 21 | Mus musculus |
| 2 | The relative uptake activity ratios of carnitine to TEA were 1.78, 11.3, and 746 for OCTN1, -2, and -3, respectively, suggesting high specificity of OCTN3 for carnitine and significantly lower carnitine transport activity of OCTN1. | Carnitine | solute carrier family 22 (organic cation transporter), member 21 | Mus musculus |
| 3 | The relative uptake activity ratios of carnitine to TEA were 1.78, 11.3, and 746 for OCTN1, -2, and -3, respectively, suggesting high specificity of OCTN3 for carnitine and significantly lower carnitine transport activity of OCTN1. | Carnitine | solute carrier family 22 (organic cation transporter), member 21 | Mus musculus |
| 4 | Thus, OCTN3 is unique in its limited tissue distribution and Na(+)-independent carnitine transport, whereas OCTN1 efficiently transported TEA with minimal expression of carnitine transport activity and may have a different role from other members of the OCTN family. | Carnitine | solute carrier family 22 (organic cation transporter), member 21 | Mus musculus |