Pub. Date : 2000 Sep 16
PMID : 11006118
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Norcantharidin-induced post-G(2)/M apoptosis is dependent on wild-type p53 gene. | norcantharidin | tumor protein p53 | Homo sapiens |
| 2 | Effort was made to investigate whether norcantharidin exerted its cytotoxicity through a p53-dependent or -independent mechanism. | norcantharidin | tumor protein p53 | Homo sapiens |
| 3 | Restoring wild-type p53 gene function in the U251 cell line after adenoviral infections induced tumor cell cytotoxicity after exposure to norcantharidin. | norcantharidin | tumor protein p53 | Homo sapiens |
| 4 | These results showed that norcantharidin kills tumor cells efficiently corresponding to their endogenous p53 gene status. | norcantharidin | tumor protein p53 | Homo sapiens |
| 5 | The results also showed the feasibility of using adenoviral p53 gene therapy to enhance chemosensitivity of tumor cells to norcantharidin. | norcantharidin | tumor protein p53 | Homo sapiens |