Title : Identification and characterization of genes responsive to apoptosis: application of DNA chip technology and mRNA differential display.

Pub. Date : 2000 Oct

PMID : 11005251






2 Functional Relationships(s)
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1 In etoposide model with chip hybridization, we defined signaling pathways that mediate apoptosis in p53 dependent manner (through activation of p53 target genes such as Waf-1/p21, PCNA, GPX, S100A2 and PTGF-beta) as well as in p53-independent manner (through activation of ODC and TGF-beta receptor, among others). Etoposide cyclin dependent kinase inhibitor 1A Homo sapiens
2 In etoposide model with chip hybridization, we defined signaling pathways that mediate apoptosis in p53 dependent manner (through activation of p53 target genes such as Waf-1/p21, PCNA, GPX, S100A2 and PTGF-beta) as well as in p53-independent manner (through activation of ODC and TGF-beta receptor, among others). Etoposide cyclin dependent kinase inhibitor 1A Homo sapiens