Title : Expression of the TGF-beta receptor gene and sensitivity to growth inhibition following polyamine depletion.

Pub. Date : 2000 Oct

PMID : 11003584






2 Functional Relationships(s)
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1 Administration of alpha-difluoromethylornithine (DFMO), a specific inhibitor of ornithine decarboxylase (the rate-limiting enzyme for polyamine synthesis), for 4 and 6 days depleted cellular polyamines putrescine, spermidine, and spermine in IEC-6 cells. Eflornithine ornithine decarboxylase 1 Rattus norvegicus
2 Administration of alpha-difluoromethylornithine (DFMO), a specific inhibitor of ornithine decarboxylase (the rate-limiting enzyme for polyamine synthesis), for 4 and 6 days depleted cellular polyamines putrescine, spermidine, and spermine in IEC-6 cells. Eflornithine ornithine decarboxylase 1 Rattus norvegicus