Title : Nuclear inclusions in oculopharyngeal muscular dystrophy consist of poly(A) binding protein 2 aggregates which sequester poly(A) RNA.

Pub. Date : 2000 Sep 22

PMID : 11001936






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This suggests that the polyalanine expansions in PABP2 induce a misfolding and aggregation of the protein into insoluble inclusions, similarly to events in neurodegenerative diseases caused by CAG/polyglutamine expansions. polyglutamine poly(A) binding protein nuclear 1 Homo sapiens