Title : Mdr1 limits CYP3A metabolism in vivo.

Pub. Date : 2000 Oct

PMID : 10999959






3 Functional Relationships(s)
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1 The average breath test (14)CO(2) area under the curves were 1.9- and 1.5-fold greater in mdr1a/1b(-/-) and mdr1a(-/-) mice, respectively, compared with (+/+) mice, and CER(max) was 2-fold greater in mdr1a/1b(-/-) compared with (+/+) mice. co(2) ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus
2 The average breath test (14)CO(2) area under the curves were 1.9- and 1.5-fold greater in mdr1a/1b(-/-) and mdr1a(-/-) mice, respectively, compared with (+/+) mice, and CER(max) was 2-fold greater in mdr1a/1b(-/-) compared with (+/+) mice. co(2) ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus
3 The average breath test (14)CO(2) area under the curves were 1.9- and 1.5-fold greater in mdr1a/1b(-/-) and mdr1a(-/-) mice, respectively, compared with (+/+) mice, and CER(max) was 2-fold greater in mdr1a/1b(-/-) compared with (+/+) mice. co(2) ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus