Title : Mechanisms underlying induction of heme oxygenase-1 by nitric oxide in renal tubular epithelial cells.

Pub. Date : 2000 Oct

PMID : 10997923






1 Functional Relationships(s)
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1 In sublytic amounts, the nitric oxide donor sodium nitroprusside induced HO-1 mRNA and protein and HO activity in a dose-dependent and time-dependent fashion; this induction was specific for nitric oxide since the nitric oxide scavenger carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide significantly reduced such induction. Nitroprusside heme oxygenase 1 Homo sapiens