Pub. Date : 2000 Oct
PMID : 10997922
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of hyperglycemia on glomerular cells may be mediated by glucose entry into the hexosamine pathway, and mesangial cell (MC) expression of the hexosamine pathway rate-limiting enzyme glutamine:fructose-6-phosphate amidotransferase (GFAT) is increased in diabetic glomerulosclerosis. | Hexosamines | glutamine--fructose-6-phosphate transaminase 1 | Homo sapiens |
| 2 | Effects of hyperglycemia on glomerular cells may be mediated by glucose entry into the hexosamine pathway, and mesangial cell (MC) expression of the hexosamine pathway rate-limiting enzyme glutamine:fructose-6-phosphate amidotransferase (GFAT) is increased in diabetic glomerulosclerosis. | Hexosamines | glutamine--fructose-6-phosphate transaminase 1 | Homo sapiens |
| 3 | Glucosamine, which is downstream of GFAT in the hexosamine pathway, produced a 2.5-fold increase in the PAI-1 promoter activity. | Hexosamines | glutamine--fructose-6-phosphate transaminase 1 | Homo sapiens |