Title : 1,25(OH)(2)-vitamin D(3) affects the subcellular distribution of protein kinase C isoenzymes in rat duodenum: influence of aging.

Pub. Date : 2000 Sep 14

PMID : 10996858






1 Functional Relationships(s)
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1 Furthermore, the ability to translocate was present in young animals after a short treatment with the phorbol ester 12-O-tetradecanoyl phorbol 13-acetate (TPA; 100 nM) or dioctanoyl-glycerol (50 microM), whereas the ability was absent in aged rats, suggesting that PKC function was impaired with aging independent of agonist stimulation. Tetradecanoylphorbol Acetate protein kinase C, alpha Rattus norvegicus