Pub. Date : 2000 Sep
PMID : 10972672
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways. | Quercetin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | CONCLUSIONS: These results suggested that (1) activation of JNK and ERKs, but not p38 kinase, is required for the H2O2-induced apoptosis; and (2) suppression of the JNK-c-Jun/AP-1 pathway and the ERK-c-Fos/AP-1 pathway is involved in the anti-apoptotic effect of quercetin. | Quercetin | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | CONCLUSIONS: These results suggested that (1) activation of JNK and ERKs, but not p38 kinase, is required for the H2O2-induced apoptosis; and (2) suppression of the JNK-c-Jun/AP-1 pathway and the ERK-c-Fos/AP-1 pathway is involved in the anti-apoptotic effect of quercetin. | Quercetin | mitogen-activated protein kinase 8 | Homo sapiens |