Title : Pharmacokinetics and antitumor properties in tumor-bearing mice of an enediol analogue inhibitor of glyoxalase I.

Pub. Date : 2000

PMID : 10972486






1 Functional Relationships(s)
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1 PURPOSE: The enediol analogue S-(N-p-chlorophenyl-N-hydroxycarbamoyl)glutathione (CHG) is a powerful, mechanism-based, competitive inhibitor of the methylglyoxal-detoxifying enzyme glyoxalase I. CHEMBL131578 glyoxalase 1 Mus musculus