Pub. Date : 2000 Aug 27
PMID : 10972232
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mechanism of action of cyclosporine and tacrolimus has been explained on the basis of their inhibition of interleukin-2 (IL-2), and induction of transforming growth factor-beta (TGF-beta). | Tacrolimus | transforming growth factor beta 1 | Homo sapiens |
| 2 | The mechanism of action of cyclosporine and tacrolimus has been explained on the basis of their inhibition of interleukin-2 (IL-2), and induction of transforming growth factor-beta (TGF-beta). | Tacrolimus | transforming growth factor beta 1 | Homo sapiens |
| 3 | RESULTS: In this study, we report that rapamycin in combination with either tacrolimus or cyclosporine significantly inhibited the lymphocyte proliferation, IL-2 expression, and induced TGF-beta, compared with these drugs alone. | Tacrolimus | transforming growth factor beta 1 | Homo sapiens |