Title : The stable pyrimidines UDPbetaS and UTPgammaS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery.

Pub. Date : 2000 Sep

PMID : 10960068






1 Functional Relationships(s)
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1 The selective P2Y(6) agonist, UDPbetaS, and the P2Y(2)/P2Y(4)-receptor agonists UTPgammaS and adenosine 5"-O-3-thiotriphosphate (ATPgammaS) were considerably more potent and efficacious (E:(max) approximately 250% of 60 mM K(+)). adenosine 5'-O-(3-thiotriphosphate) purinergic receptor P2Y2 Rattus norvegicus