Pub. Date : 2000 Sep
PMID : 10952785
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | dUTPase catalyses the hydrolysis of dUTP to dUMP, thereby maintaining low intracellular dUTP. | deoxyuridine triphosphate | Deoxyuridine triphosphatase | Drosophila melanogaster |
| 2 | There was a striking variation in the amount of dUTP formed following exposure to ZD9331 (between 1.3 and 57 pmole 10(-6)cells) and was in general inversely associated with dUTPase activity. | deoxyuridine triphosphate | Deoxyuridine triphosphatase | Drosophila melanogaster |
| 3 | A large expansion in the dUTP pool was associated with increased sensitivity to a 24-h exposure to ZD9331 in A549 cells that have low dUTPase activity/expression. | deoxyuridine triphosphate | Deoxyuridine triphosphatase | Drosophila melanogaster |