Title : Antiproliferative properties of sphingosine 1-phosphate in human hepatic myofibroblasts. A cyclooxygenase-2 mediated pathway.

Pub. Date : 2000 Nov 3

PMID : 10942778






1 Functional Relationships(s)
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1 We conclude that S1P inhibits proliferation of hMF, probably via an intracellular mechanism, through early COX-2-dependent release of prostaglandin E(2) and cAMP, and delayed COX-2 induction. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens