Title : Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes. HOE 901/3002 Study Group.

Pub. Date : 2000 Aug

PMID : 10937510






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1 Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes. Insulin Glargine insulin Homo sapiens
2 We compared the efficacy and safety of glargine (a long-acting insulin analog) and NPH insulins in insulin-naive type 2 diabetic patients treated with oral antidiabetic agents. Insulin Glargine insulin Homo sapiens
3 CONCLUSIONS: Use of insulin glargine compared with NPH is associated with less nocturnal hypoglycemia and lower post-dinner glucose levels. Insulin Glargine insulin Homo sapiens
4 These data are consistent with peakless and longer duration of action of insulin glargine compared with NPH. Insulin Glargine insulin Homo sapiens
5 These data support use of insulin glargine instead of NPH in insulin combination regimens in type 2 diabetes. Insulin Glargine insulin Homo sapiens