Title : Regulation of c-myc mRNA decay in vitro by a phorbol ester-inducible, ribosome-associated component in differentiating megakaryoblasts.

Pub. Date : 2000 Oct 27

PMID : 10931849






2 Functional Relationships(s)
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Protein Name
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1 TPA-induced differentiation of K562 cells causes rapid down-regulation of c-myc expression, due in part to an mRNA decay rate that is 4-fold faster compared with dividing cells. Tetradecanoylphorbol Acetate MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 A cell-free mRNA decay system reconstitutes TPA-induced destabilization of c-myc mRNA, but it requires at least two components for reconstitution. Tetradecanoylphorbol Acetate MYC proto-oncogene, bHLH transcription factor Homo sapiens