Title : Induction of functional CD154 (CD40 ligand) in neonatal T cells by cAMP-elevating agents.

Pub. Date : 2000 Aug

PMID : 10929069






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Induction of functional CD154 (CD40 ligand) in neonatal T cells by cAMP-elevating agents. Cyclic AMP CD40 ligand Homo sapiens
2 Induction of functional CD154 (CD40 ligand) in neonatal T cells by cAMP-elevating agents. Cyclic AMP CD40 ligand Homo sapiens
3 In the present report we describe that CD45RA+ newborn cells are able to synthesize and express CD154 at similar or even higher levels than adult cells in response to ionomycin and cAMP-elevating agents which trigger the protein kinase A (PKA) -mediated metabolic pathway. Cyclic AMP CD40 ligand Homo sapiens
4 Surface levels of CD154 did not correlate with specific mRNA concentration, indicating that dibutyryl cAMP up-regulates CD154 by acting at a post-transcriptional stage. Cyclic AMP CD40 ligand Homo sapiens
5 Surface levels of CD154 did not correlate with specific mRNA concentration, indicating that dibutyryl cAMP up-regulates CD154 by acting at a post-transcriptional stage. Cyclic AMP CD40 ligand Homo sapiens