Title : Evidence that the substrate backbone conformation is critical to phosphorylation by p42 MAP kinase.

Pub. Date : 2000 Jul 28

PMID : 10922466






1 Functional Relationships(s)
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1 The proline-directed p42 mitogen-activated protein kinase (ERK2) was used to phosphorylate the serine side chain in Pro-Arg-Ser-Pro-Phe-4-nitroanilide under conditions where different amounts of cis prolyl isomer of the substrate were present. Proline mitogen-activated protein kinase 1 Homo sapiens