Title : Antigene and antiproliferative effects of a c-myc-targeting phosphorothioate triple helix-forming oligonucleotide in human leukemia cells.

Pub. Date : 2000 Jul 15

PMID : 10919652






1 Functional Relationships(s)
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1 The purpose of the present work was to characterize the antigene and antiproliferative activity of a triple helix-forming oligonucleotide (TFO) targeted to a homopurine-homopyrimidine sequence in the P2 promoter of the c-myc gene. tfo MYC proto-oncogene, bHLH transcription factor Homo sapiens