Title : MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping.

Pub. Date : 2000 Aug 4

PMID : 10918072






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The MDR3 P-glycoprotein is a transmembrane protein that translocates phosphatidylcholine. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
2 MDR3 P-glycoprotein-dependent transport of a short-chain phosphatidylcholine analog and drugs was inhibited by several MDR reversal agents and other drugs, indicating an interaction between these compounds and MDR3 P-gp. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
3 MDR3 P-glycoprotein-dependent transport of a short-chain phosphatidylcholine analog and drugs was inhibited by several MDR reversal agents and other drugs, indicating an interaction between these compounds and MDR3 P-gp. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens