Title : Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene.

Pub. Date : 2000 Jul 1

PMID : 10910056






2 Functional Relationships(s)
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Protein Name
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1 Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene. anthracene cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus
2 This investigation demonstrates that CYP1B1 null mice are almost completely protected from the acute bone marrow cytotoxic and preleukemic effects of the prototypic PAH 7,12-dimethylbenz[a]anthracene (DMBA). anthracene cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus