Title : Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia.

Pub. Date : 2000 Jul

PMID : 10909895






3 Functional Relationships(s)
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1 In this report, we present evidence that terbutaline, a beta2-agonist, inhibits TNFalpha production and enhances interleukin-10 (IL-10) release in the anesthetized rat treated with LPS. Terbutaline interleukin 10 Rattus norvegicus
2 In this report, we present evidence that terbutaline, a beta2-agonist, inhibits TNFalpha production and enhances interleukin-10 (IL-10) release in the anesthetized rat treated with LPS. Terbutaline interleukin 10 Rattus norvegicus
3 These findings suggest that the inhibition of TNFalpha and NO (via iNOS) production as well as the increment of IL-10 production contribute to the beneficial effect of terbutaline in animals with endotoxic shock. Terbutaline interleukin 10 Rattus norvegicus