Title : Generation of cyclic guanosine monophosphate by heme oxygenases in the human testis--a regulatory role for carbon monoxide in Sertoli cells?

Pub. Date : 2000 Aug

PMID : 10906077






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Treatments of isolated tubules with either sodium arsenite, known to induce HO-1, or hematin, an HO substrate, resulted in 4.4- and 1.8-fold, respectively, increases in cGMP levels. Cyclic GMP heme oxygenase 1 Homo sapiens
2 These findings, demonstrating for the first time a link between HO-1 activity in Sertoli cells and sGC-dependent cGMP production in seminiferous tubules, suggest a functional role of CO in the human testis. Cyclic GMP heme oxygenase 1 Homo sapiens