Title : Bradykinin B(2) receptor antagonism attenuates blood pressure response to acute angiotensin-converting enzyme inhibition in normal men.

Pub. Date : 2000 Jul

PMID : 10904025






2 Functional Relationships(s)
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1 The bradykinin antagonist icatibant (10 mg IV) was coadministered over the first 15 minutes of a 2-hour infusion of the ACE inhibitor perindoprilat (1.5 mg IV). perindoprilat angiotensin I converting enzyme Homo sapiens
2 Perindoprilat inhibited ACE activity and elicited the expected changes in active renin concentration and angiotensin peptides. perindoprilat angiotensin I converting enzyme Homo sapiens