Pub. Date : 2000 Feb
PMID : 10877531
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The involvement of alpha2-adrenoceptors in the antinociception induced by the tricyclic antidepressants amitriptyline and imipramine was investigated in mice by using the hot-plate and abdominal constriction tests. | Imipramine | adrenergic receptor, alpha 2a | Mus musculus |
| 2 | On the basis of the above data, it can be postulated that amitriptyline and imipramine exerted their antinociceptive effect by activation of alpha2-adrenoceptors. | Imipramine | adrenergic receptor, alpha 2a | Mus musculus |