Pub. Date : 2000 Jun 15
PMID : 10861791
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |
| 2 | We hypothesized that treatments with haloperidol or risperidone will affect synthesis/release of brain BDNF and tested this hypothesis by measuring BDNF and TrkB in rat brain regions after a 29-day-treatment with haloperidol or risperidone added to chow. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |
| 3 | We hypothesized that treatments with haloperidol or risperidone will affect synthesis/release of brain BDNF and tested this hypothesis by measuring BDNF and TrkB in rat brain regions after a 29-day-treatment with haloperidol or risperidone added to chow. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |
| 4 | We hypothesized that treatments with haloperidol or risperidone will affect synthesis/release of brain BDNF and tested this hypothesis by measuring BDNF and TrkB in rat brain regions after a 29-day-treatment with haloperidol or risperidone added to chow. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |
| 5 | Both haloperidol and risperidone significantly decreased BDNF concentrations in frontal cortex, occipital cortex and hippocampus and decreased or increased TrkB receptors in selected brain structures. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |