Title : Acid potentiation of the capsaicin receptor determined by a key extracellular site.

Pub. Date : 2000 Jul 5

PMID : 10859346






1 Functional Relationships(s)
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1 The response of VR1 to capsaicin or noxious heat is dynamically potentiated by extracellular protons within a pH range encountered during tissue acidosis, such as that associated with arthritis, infarction, tumor growth, and other forms of injury. Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens