Title : Retroviral expression of the hepatitis B virus x gene promotes liver cell susceptibility to carcinogen-induced site specific mutagenesis.

Pub. Date : 2000 Jun 30

PMID : 10856831






1 Functional Relationships(s)
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Protein Name
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1 AGG to AGT transversion in codon 249 of exon 7 of the p53 gene occurs in over 50% of HCC from endemic regions, where both chronic infection with the hepatitis B virus (HBV) and exposure to carcinogens such as aflatoxin B1 (AFB1) prevail. Aflatoxin B1 tumor protein p53 Homo sapiens