Title : Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents.

Pub. Date : 2000 Jun

PMID : 10854324






1 Functional Relationships(s)
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1 This NO-mediated increase in enzymatically active DNA-PK not only protects cells from the toxic effects of NO, but also provides crossprotection against clinically important DNA-damaging agents, such as X-ray radiation, adriamycin, bleomycin and cisplatin. Bleomycin protein kinase, DNA-activated, catalytic subunit Homo sapiens