Title : The effect of itraconazole on the pharmacokinetics and pharmacodynamics of oral prednisolone.

Pub. Date : 2000 Apr

PMID : 10853878






1 Functional Relationships(s)
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1 The susceptibility of prednisolone to interact with CYP3A4 inhibitors is considerably smaller than that of methylprednisolone, and itraconazole and probably also other inhibitors of CYP3A4 can be used concomitantly with prednisolone without marked changes in the effects of this corticosteroid. Itraconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens