Pub. Date : 2000 May 1
PMID : 10841949
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Histamine, an important inflammatory mediator in allergic diseases and asthma, was reported to have modulatory effects on T cells by down-regulating Th1-type cell cytokines like interleukin 2 (IL-2) and interferon-gamma (IFN-gamma). | Histamine | interferon gamma | Homo sapiens |
| 2 | Histamine, an important inflammatory mediator in allergic diseases and asthma, was reported to have modulatory effects on T cells by down-regulating Th1-type cell cytokines like interleukin 2 (IL-2) and interferon-gamma (IFN-gamma). | Histamine | interferon gamma | Homo sapiens |
| 3 | In this study we examined the effect of histamine and the histamine-receptor antagonists cimetidine and diphenhydramine on the production of neopterin after stimulation with IFN-gamma in the myelomonocytoma cell line THP-1. | Histamine | interferon gamma | Homo sapiens |
| 4 | Increasing concentrations of histamine markedly suppressed IFN-gamma induced neopterin formation. | Histamine | interferon gamma | Homo sapiens |
| 5 | Our results suggest, that histamine may be a potent inhibitor of effects or mechanisms induced by IFN-gamma in monocytes/macrophages. | Histamine | interferon gamma | Homo sapiens |