Title : Angiotensin II type 1 receptor antagonist (losartan) down-regulates transforming growth factor-beta in experimental acute pyelonephritis.

Pub. Date : 2000 Jul

PMID : 10840457






1 Functional Relationships(s)
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1 In animals treated with losartan, kidney TGF-beta, IFN-gamma and IL-6 decreased significantly at 3 and 8 weeks as compared with controls, untreated or those treated with NaCl, (p <0.005 respectively). Losartan transforming growth factor, beta 1 Mus musculus