Title : Development of an In Vitro Screening Assay for Compounds that Increase Bone Formation.

Pub. Date : 1999

PMID : 10838433






1 Functional Relationships(s)
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1 Of the compounds tested, only PTH, prostaglandin E(2), 8-bromo-cAMP, and forskolin induced c-fos mRNA levels, indicating that this assay was specific for compounds that are known to induce cAMP and stimulate bone growth. Colforsin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus