Title : Desensitisation of protease-activated receptor-1 (PAR-1) in rat astrocytes: evidence for a novel mechanism for terminating Ca2+ signalling evoked by the tethered ligand.

Pub. Date : 2000 Jun 1

PMID : 10835036






1 Functional Relationships(s)
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1 In rat primary astrocytes, short-term stimulation with thrombin resulted in a single [Ca2+]i transient and a dose-dependent de- and resensitisation, as assessed by single-cell Ca2+ imaging of fura-2-loaded astrocytes. Fura-2 coagulation factor II Rattus norvegicus