Pub. Date : 2000 Jun
PMID : 10834930
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Catecholamines up-regulate lipopolysaccharide-induced IL-6 production in human microvascular endothelial cells. | Catecholamines | interleukin 6 | Homo sapiens |
| 2 | Whereas catecholamines decrease the LPS-induced production of IL-6 by leukocytes, serum levels of IL-6 are dramatically increased by the catecholamine epinephrine in animal endotoxemia models. | Catecholamines | interleukin 6 | Homo sapiens |
| 3 | Furthermore, these catecholamines could even potentiate the LPS-induced IL-6 protein production. | Catecholamines | interleukin 6 | Homo sapiens |
| 4 | The catecholamine-induced IL-6 stimulation is based on increased IL-6 mRNA levels. | Catecholamines | interleukin 6 | Homo sapiens |
| 5 | The catecholamine-induced IL-6 stimulation is based on increased IL-6 mRNA levels. | Catecholamines | interleukin 6 | Homo sapiens |
| 6 | Thus, endothelial cells might be a possible source of increased IL-6 production observed in situations such as stress or septic shock, in which catecholamines are elevated due to endogenous production or exogenous application. | Catecholamines | interleukin 6 | Homo sapiens |