Title : Enhanced endothelin ET(B) receptor down-regulation in human tumor cells.

Pub. Date : 2000 May 12

PMID : 10822048






1 Functional Relationships(s)
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1 Staurosporine, a wide spectrum protein kinase inhibitor, significantly reduced, and N-[N-[N-[2, 6-dimethyl-1piperidinyl)carbonyl]-4-Me-L-Leu]-1-(methoxycarbonyl)- D-t ryptophanyl]-D-norleucine (BQ788), an endothelin ET(B) receptor antagonist, attenuated the down-regulation of endothelin receptors induced by endothelin receptor agonists. Staurosporine endothelin 1 Homo sapiens