Pub. Date : 2000 Jun
PMID : 10820139
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil. | Modafinil | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | The ability of modafinil to affect human hepatic cytochrome P450 (CYP) activities was examined in vitro. | Modafinil | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 3 | The ability of modafinil to affect human hepatic cytochrome P450 (CYP) activities was examined in vitro. | Modafinil | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 4 | Modafinil exhibited minimal capacity to inhibit any CYP enzyme, except CYP2C19. | Modafinil | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 5 | The potential for induction of CYP activity was evaluated by exposing primary cultures of human hepatocytes to modafinil (10-300 microM). | Modafinil | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |